Mattia Bernetti / Ricercatore Legge 240/10 a tempo determinato
CHEM-07/A 03/CHEM-07 Chimica farmaceutica
| Struttura | ||||
| Dipartimento di Scienze Biomolecolari (DISB) | Urbino Piazza Rinascimento, 6 | mattia.bernetti@uniurb.it | ||
| Curriculum | |
Mattia Bernetti is a fixed-term researcher, type B (RTD-B), at the Department of Biomolecular Sciences of the University of Urbino.
Mattia graduated in Chemistry and Pharmaceutical Technologies at University of Bologna in 2014, with a thesis work in computational chemistry conducted in the group of Prof. Jorgensen at Yale University, CT, USA. He obtained the Ph.D. in Biotechnological and Pharmaceutical Sciences from the University of Bologna in 2018, working in the group of Prof. Cavalli and spending six months abroad in the lab of Prof. Amaro at the University of California San Diego, CA, USA.
As a postdoctoral fellow, he joined for three years the Molecular and Statistical Biophysics group at Scuola Internazionale Superiore di Studi Avanzati (SISSA) in Trieste, working under the mentorship of Prof. Bussi. Subsequently, he continued post-doctoral research for an additional three years in the Computational and Chemical Biology unit at the Istituto Italiano di Tecnologia (IIT) in Genova, led by Prof. Cavalli.
Mattia has experience in the use of computational methods, particularly molecular dynamics (MD) simulations, to characterize structure and dynamics of pharmaceutically relevant biomolecules, including the emerging class of non-coding RNAs.
- Bernetti, M.,* Bosio, S., Bresciani, V., Falchi, F., Masetti, M.* Probing allosteric communication with combined molecular dynamics simulations and network analysis, COSB, 2024, 86:102820.
- Bosio, S., Bernetti, M.,* Rocchia, W., Masetti, M., Similarities and Differences in Ligand Binding to Protein and RNA Targets: The Case of Riboflavin, J. Chem. Inf. Model., 2024, 64, 11, 4570–4586.
- Aguti, R., Bernetti, M.,* Bosio, S., Decherchi, S., Cavalli A., On the allosteric puzzle and pocket crosstalk through computational means, J. Chem. Phys., 2023, 158 (16), 165101-165101.
- Bernetti, M. and Bussi, G., Integrating experimental data with molecular simulations to investigate RNA structural dynamics, COSB, 2023.
- Bernetti, M.,* Aguti, R., Bosio, S., Recanatini, M., Masetti, M., Cavalli, A.,* Computational drug discovery under RNA times, QRB Discov., 2022.
- Bernetti, M.,* Hall, K.B., Bussi, G.,* Reweighting of molecular simulations with explicit-solvent SAXS restraints elucidates ion-dependent RNA ensembles, NAR, 2021, 49 (14): e84.
- Bernetti, M., Bertazzo, M., Masetti, M., Data-Driven Molecular Dynamics: A Multifaceted Challenge, Pharmaceuticals, 2020, 13: 253.
- Bernetti, M. and Bussi, G., Pressure control using stochastic cell rescaling, J. Chem. Phys., 2020, 153: 114107.
Prodotti della Ricerca di Mattia Bernetti.
