The aim of the course is to give the basic knowledge to assign the structural formula of unknown organic compound through the combined IR, 1H and 13C-NMR, and Mass analysis.

Elemental composition and molecular formula
- Elemental analysis
- Mass spectrometry: Introduction and theory, the mass spectrum, recognition of the molecular ion peak, fragmentation, rearrangements
- degree of unsaturation
Relations between the atoms of the organic molecules
Molecular structure
- 1H-NMR Spectrometry: Introduction and theory, chemical shift, spin-spin coupling, equivalence, coupling constants, spin systems, long-range coupling, spin decoupling
- 13C-NMR Spectrometry: chemical shift, off-resonance spectra, DEPT e APT
- NMR-2D Spectrometry: 1H-1H COSY correlation, 1H-13C HETCOR correlation and HMQC, HMBC, 13C-13C INADEQUATE correlation
Identification of the main functional groups of organic substances
- IR Spectrometry

- The student must show the possession of basic knowledge of modern methods of spectroscopic investigation as well as the understanding of the fundamental characteristics of the spectra provided by each substance (NMR, IR and Mass).
- The student must show the ability to apply the knowledge, and the ability to identify the presence of molecular fragments of varying complexity in order to define how these fragments are linked together, through the combined analysis of spectra obtained with the various techniques. The student must be able to simulate the spectra of new molecules and able to identify which methods are most useful to resolve a particular structural problem.
- The student must be able to clearly communicate the knowledge and the ability to interpret the various spectra to specialists and not.
- The student, at the end of the course, will have developed a good autonomy for the identification of the structures of unknown organic molecules.
 

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

Course books

- Robert M. Silverstein, Francis X. Webster; David J. Kiemle, David L. Bryce; "Spectrometric Identification of Organic Compounds" 8th Edition, Wiley
- lecture SLIDES

The frequency at lectures and exercises is strongly recommended