GENERAL PHARMACOLOGY AND PHARMACOTHERAPY I
FARMACOLOGIA GENERALE E FARMACOTERAPIA I
| A.Y. | Credits |
|---|---|
| 2021/2022 | 10 |
| Lecturer | Office hours for students | |
|---|---|---|
| Piero Sestili | At the end of each lesson. By appointment when the teaching course is completed. |
| Teaching in foreign languages |
|---|
|
Course with optional materials in a foreign language
English
This course is entirely taught in Italian. Study materials can be provided in the foreign language and the final exam can be taken in the foreign language. |
Assigned to the Degree Course
| Date | Time | Classroom / Location |
|---|
| Date | Time | Classroom / Location |
|---|
Learning Objectives
The aim of the course is to provide knowledge about routes of administration, metabolism, distribution, and elimination of synthetic and plant-derived drugs as well as the basic concepts of their therapeutic and adverse effects. In the second part of the course, attention will be devoted to the study of the antibiotics and chemotherapeutic drugs used in antibacteria, antiviral, antimicotic and anticancer drugs..
Program
PHARMACOLOGY: general principles: drug, medicine and poison.
Pharmacokinetics: Physicochemical factors in transfer of drugs across membranes. Drug absorption, bioavailability, and routes of administration. Distribution of drugs. Biotransformation of drugs. Excretion of drugs. Clinical pharmacokinetics.
Pharmacodynamics: Mechanisms of drug action. Drug receptors. Receptors for physiological regulatory molecules. Quantitation of drug-receptor interactions. Dose-effect relationship.
CHEMOTHERAPY
General issues of antimicrobial therapy. Bacterial resistance. Disinfection and sterilization. Sulfonamides and quinolones. Beta-lactam antibiotics, penicillins and cephalosporins. Other cell wall inhibitors Aminoglycosides. Protein synthesis inhibitors. Chemotherapy of tuberculosis. Antifungal agents. Antiviral and antiretroviral agents. Therapy of COVID-19. Antineoplastic agents. Chemotherapy of protozoal infections (malaria, amebiasis, trichomoniasis, trypanosomiasis).
Bridging Courses
I is highly recommended to have passed the exams of Biochemistry and Human Physiology
Learning Achievements (Dublin Descriptors)
At the end of the course, students should demonstrate
a robust knowledge and competence about: a) the principles of general pharmacology; b) the principles of chemo-antiobiotic therapy c) the different classes of antibiotics and chemotherapeutic agents and their therapeutic use in relation to type of the infection/infestion or of the type of tumor. (Knowledge and understanding);
-the scientific background needed to evaluate and solve the problems regarding the general principles of drug use and prescription, and those pertining to the classes the chemo-antibiotic agents in a professional setting. (Applying knowledge patience and understanding)
-critical and competent assessment capacity: i.e. the ability to integrate their own knowledge and make judgments in theoretical situations or complex practices with regard to the issues typical of the discipline, (Making judgments)
- the ability to communicate the acquired knowledge in general pharmacology and chemo-antibiotic therapy in a clear, essential and scientifically correct shape (Communication);
- demonstrate the ability to develop their own learning with autonomy and critical sense. This ability will be encouraged during the entire course by the teacher and will be evaluated on examination
(Learning skills).
Teaching Material
The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it
Teaching, Attendance, Course Books and Assessment
- Teaching
Frontal lessons
- Attendance
None
- Course books
- H.P. Rang, J.M. Ritter, R.J. Flower, G. Henderson. "Farmacologia". Ottava edizione
- as an alternative: R. Levine "Farmacologia. Azioni e reazioni dei farmaci" EMSI
Both the textbooks are available in English
- Assessment
Oral exam
- Disabilità e DSA
Le studentesse e gli studenti che hanno registrato la certificazione di disabilità o la certificazione di DSA presso l'Ufficio Inclusione e diritto allo studio, possono chiedere di utilizzare le mappe concettuali (per parole chiave) durante la prova di esame.
A tal fine, è necessario inviare le mappe, due settimane prima dell’appello di esame, alla o al docente del corso, che ne verificherà la coerenza con le indicazioni delle linee guida di ateneo e potrà chiederne la modifica.
Additional Information for Non-Attending Students
- Attendance
None
- Course books
- H.P. Rang, J.M. Ritter, R.J. Flower, G. Henderson. "Farmacologia". Ottava edizione
- as an alternative: R. Levine "Farmacologia. Azioni e reazioni dei farmaci" EMSI
Both the textbooks are available in English
- Assessment
Oral exam
- Disabilità e DSA
Le studentesse e gli studenti che hanno registrato la certificazione di disabilità o la certificazione di DSA presso l'Ufficio Inclusione e diritto allo studio, possono chiedere di utilizzare le mappe concettuali (per parole chiave) durante la prova di esame.
A tal fine, è necessario inviare le mappe, due settimane prima dell’appello di esame, alla o al docente del corso, che ne verificherà la coerenza con le indicazioni delle linee guida di ateneo e potrà chiederne la modifica.
| « back | Last update: 30/06/2021 |
