Matteo Micucci / Professore Associato

Matteo Micucci (Cesena, 1983) svolge attività di ricerca nel settore scientifico disciplinare chim10 (Chimica degli Aliment). Ha studiato “Farmacia e Farmacia Industriale” presso l’Università di Bologna, laureandosi  con 110/110 e lode discutendo una tesi sperimentale dal titolo “Aspetti chimico-farmaceutici e attività spasmolitica di alcuni principi attivi contenuti nella Solenostemma Argel”
Nella stessa Università, ha conseguito il Dottorato di Ricerca Europeo in Scienze Farmaceutiche, in data 20/04/2012.

Ha svolto attività di Ricerca presso il Laboratorio di Ricerca coordinato dal Dr. Randolph Arroo, De Montfort University (Leicester, UK) dedicandosi all'acquisizione di tecniche di estrazione e isolamento di principi attivi da matrici vegetali. 

La sua produzione scientifica è testimoniata da numerose pubblicazioni su autorevoli riviste di rilievo internazionale, nonchè dalle sue relazioni in congressi nazionali ed internazionali.

1.      Micucci M, Battistelli M, Burattini S, Mari M, Retini M, Osman R, Versari I, Stella AB, Gianfanti F, Udodinma JO, Onesimo F, Riela S, Canale M, Piccionello AP, Faenza I, Salucci S. Food Waste to Wellness: A Grape Pomace Blend in Gastric Cancer Prevention. Food Sci Nutr. 2025 May 30;13(6): e70350. doi: 10.1002/fsn3.70350.

2.      Grassi E, Cocozza di Montanara A, Battistelli M, Micucci M, Guidi L, Gianfanti F, Baldrighi E, Catani L, Sandulli R, Semprucci F, Caenorhabditis elegans in the research of plants-derived nutraceuticals: a VOSviewer-based trend analysis, Heliyon, 2025, 11, 13, e43595. https://doi.org/10.1016/j.heliyon.2025.e43595

3.      Okeke UJ, Micucci M, Mihaylova D, Cappiello A. The effects of experimental conditions on extraction of polyphenols from African Nutmeg peels using NADESs-UAE: a multifactorial modelling technique. Sci Rep. 2025; 15(1):4890.  ISBN or DOI:  10.1038/s41598-025-88233-8.

4.      Agostini, D., Bartolacci, A., Rotondo, R., De Pandis, M. F., Battistelli, M., Micucci, M., Potenza, L., Polidori, E., Ferrini, F., Sisti, D., Pegreffi, F., Pazienza, V., Virgili, E., Stocchi, V., & Donati Zeppa, S. Homocysteine, Nutrition, and Gut Microbiota: A Comprehensive Review of Current Evidence and Insights. Nutrients. 2025;17(8):1325.

5.      Okeke, U.J.; Micucci, M.; Mihaylova, D.; Cappiello, A. Synthesis and Application of Natural Deep Eutectic Solvents (NADESs) for Upcycling Horticulture Residues. Horticulturae 2025, 11, 439. https://doi.org/10.3390/horticulturae11040439

6.      Burattini, S., Gianfanti, F., Onesimo, F., Zeppa, S.D., Canonico, B., Montanari, M., Panza, G., Lopez, D., Annibalini, G., Fanelli, F., Saltarelli, R., Mari, M., Retini, M., Osman, R., Mariam, A., Micucci, M., Caprioli, G., Santanatoglia, A., Agostini, D.,  Battistelli, M. Blue elixir of youth and wellness: The multicomponent-multitarget paradigm of Curcuma caesia Roxb. Journal of Functional Foods, 2025, ISBN or DOI: 10.1016/j.jff.2025.106699

7.      Micucci M, Gianfanti F, Donati Zeppa S, Annibalini G, Canonico B, Fanelli F, Saltarelli R, Osman R, Montanari M, Lopez D, Nasoni G, Panza G, Bargagni E, Luchetti F, Retini M, Mari M, Zappia G, Stocchi V, Bartolacci A, Burattini S and Battistelli M (2025) Q-Der: a next-generation CoQ10 analogue supercharging neuroprotection by combating oxidative stress and enhancing mitochondrial function. Front. Mol. Biosci. 12:1525103. ISBN or DOI: 10.3389/fmolb.2025.1525103

8.      Garcia-Merino JA, Carrabs V, Ferrini F, Salucci S, Battistelli M, Burattini S, Luchetti F, Nasoni MG, Annibalini G, Micucci M, Gianfanti F, Sestili P, Larrosa M, Barbieri E. Revitalizing Muscle Regeneration: Cocoa Polyphenols Shield Mitochondrial Integrity and Boost Myogenesis Under Oxidative Stress. Microsc Res Tech. 2025; 88(3): 905-912. ISBN or DOI: 10.1002/jemt.24755.

9.      Donati Zeppa S, Micucci M, Ferrini F, Gioacchini AM, Piccoli G, Potenza L, Bartolacci A, Annibalini G, Abdur Rehman A, Calcabrini C, Stocchi V, Sestili P. Differential Cytotoxic Effects of Garcinia mangostana Pericarp Extract on Leukemic versus Normal Human Cell Lines: Insights into Selective Anticancer Activity., Journal of Herbal Medicine, 2024; 48, 100937. ISBN or DOI: https://doi.org/10.1016/j.hermed.2024.100937

10. Bertuccioli A, Cardinali M, Micucci M, Rocchi MBL, Palazzi CM, Zonzini GB, Annibalini G, Belli A, Sisti D. Efficacy of Streptococcus salivarius Blis K12 in the Prevention of Upper Respiratory Tract Infections in Physically Active Individuals: A Randomized Controlled Trial. Microorganisms. 2024; 12(11): 2164. ISBN or DOI: 10.3390/microorganisms12112164. PMID: 39597553

11. Budriesi R, Corazza I, Roncioni S, Scanferlato R, De Luca D, Marzetti C, Gotti R, Rizzardi N, Bergamini C, Micucci M, Roncarati D, Mattioli LB. Herbal Extracts Mixed with Essential Oils: A Network Approach for Gastric and Intestinal Motility Disorders. Nutrients. 2024;16(24):4357. ISBN or DOI: 10.3390/nu16244357

12. Micucci M, Xiang BZ, Ting CM, Kwan HY, Mari M, Retini M, Burattini S, Osman R, Okeke UJ, Abdullah FO, Gianfanti F, Battistelli M Matching traditional Chinese medicine and western medicine-based research: Advanced nutraceutical development for proactive gastric cancer prevention, World J Gastrointest Oncol, 2024;16(9): 3798-3819.    ISBN or DOI: 10.4251/wjgo.v16.i9.3798

13. Scarpa ES, Antonelli A, Balercia G, Sabatelli S, Maggi F, Caprioli G, Giacchetti G, Micucci M. Antioxidant, anti-inflammatory, anti-diabetic, and pro-osteogenic activities of polyphenols for the treatment of two different chronic diseases: type 2 diabetes mellitus and osteoporosis, Biomolecules, 2024, 14(7):83.  ISBN or DOI:  10.3390/biom14070836.               

14. Mattioli LB, Frosini M, Corazza I, Fiorino S, Zippi M, Micucci M, Budriesi R. Long COVID-19 gastrointestinal related disorders and traditional Chinese medicine: A network target-based approach. Phytother Res. 2024, 38(5), 2323-2346. ISBN or DOI:  10.1002/ptr.8163

15. Micucci M, Gioacchini S, Baggieri M, Fioravanti R, Bucci P, Giuseppetti R, Saleem S.S., Sazan Maulud Q., Fuad O. Abdullah, Ismael Badr Q., Ahmed J. Q., D'Ugo E., Marchi A., Okeke U. J., Magurano F. Review from host and guest approach to new frontiers nutraceuticals in the era of COVID-19, Future Foods. 2024, 9, 100303. ISBN or DOI: https://doi.org/10.1016/j.fufo.2024.100303.

16. Micucci M, Stella Bartoletti A, Abdullah FO, Burattini S, Versari I, Canale M, D'Agostino F, Roncarati D, Piatti D, Sagratini G, Caprioli G, Mari M, Retini M, Faenza I, Battistelli M, Salucci S. Paradigm Shift in Gastric Cancer Prevention: Harnessing the Potential of Aristolochia olivieri Extract. Int J Mol Sci. 2023, 24(21), 16003.  ISBN or DOI: 10.3390/ijms242116003

17. Magurano F, Micucci M, Nuzzo D, Baggieri M, Picone P, Gioacchini S, Fioravanti R, Bucci P, Kojouri M, Mari M, Retini M, Budriesi R, Mattioli LB, Corazza I, Di Liberto V, Todaro L, Giuseppetti R, D'Ugo E, Marchi A, Mecca M, D'Auria M. A potential host and virus targeting tool against COVID-19: Chemical characterization, antiviral, cytoprotective, antioxidant, respiratory smooth muscle relaxant effects of Paulownia tomentosa Steud. Biomed Pharmacother. 2023, 158, 114083. ISBN or DOI: 10.1016/j.biopha.2022.114083

18. Bidgoli R. D., Abdullah, F. O., Budriesi R., Beatrice Mattioli, L., Spadoni G., Mari M., Micucci, M. Essential oil Chemical Composition, Antioxidant and Antibacterial Activities of Eucalyptus largiflorens F. Muell. Polish Journal of Environmental Studies. 2023, 32(4), 3043-3052. ISBN or DOI: https://doi.org/10.15244/pjoes/161886

19. Fontana R, Mattioli LB, Biotti G, Budriesi R, Gotti R, Micucci M, Corazza I, Marconi P, Frosini M, Manfredini S, Buzzi R, Vertuani S. Magnolia officinalis L. bark extract and respiratory diseases: From traditional Chinese medicine to western medicine via network target. Phytother Res. 2023, 37(7), 2915-2938. ISBN or DOI: 10.1002/ptr.7786

20. Das G, Budriesi R, Shin HS, Urso F, Bose S, Banerjee S, Del Pilar Rodriguez-Torres M, Mattioli LB, Patra JK, Micucci M. Nutraceuticals, a Bridge Between Past and Future: Focus on Mushrooms Biological Activities and Myco-Chemistry. Mini Rev Med Chem. 2023;23(3), 320-335. ISBN or DOI: 10.2174/1389557522666220622104845

21. Mattioli LB, Corazza I, Micucci M, Pallavicini M, Budriesi R. Tannins-Based Extracts: Effects on Gut Chicken Spontaneous Contractility. Molecules. 2023, 28(1), 395 ISBN or DOI:  10.3390/molecules28010395.

22. Micucci M., Budriesi R., Mandrioli M., Tura M., Corazza I., Frosini M., Aldini R., Mattioli LB, Gallina Toschi T. Effects of turmeric powder on intestinal and biliary functions: The influence of curcuminoids concentration on spontaneous contractility, J. Funct. Foods. 2022, 99, 105314. ISBN or DOI: https://doi.org/10.1016/j.jff.2022.105314

23. Curci F, Corbo F, Clodoveo ML, Salvagno L, Rosato A, Corazza I, Budriesi R, Micucci M, Mattioli LB. Polyphenols from Olive-Mill Wastewater and Biological Activity: Focus on Irritable Bowel Syndrome. Nutrients. 2022, 14(6), 1264. ISBN or DOI:  10.3390/nu14061264

24. Mattioli LB, Frosini M, Amoroso R, Maccallini C, Chiano E, Aldini R, Urso F, Corazza I, Micucci M, Budriesi R. Olea europea L. Leaves and Hibiscus sabdariffa L. Petals Extracts: Herbal Mix from Cardiovascular Network Target to Gut Motility Dysfunction Application. Nutrients. 2022, 14(3), 463. ISBN or DOI: 10.3390/nu14030463

25. Chiaino E, Stella R, Peggion C, Micucci M, Budriesi R, Mattioli LB, Marzetti C, Pessina F, Valoti M, Frosini M. Acacia catechu Willd. Extract Protects Neuronal Cells from Oxidative Stress-Induced Damage. Antioxidants (Basel). 2022, 1(1):81. ISBN or DOI: 10.3390/antiox11010081

26. Chiaino E, Micucci M, Budriesi R, Mattioli LB, Marzetti C, Corsini M, Frosini M. Hibiscus Flower and Olive Leaf Extracts Activate Apoptosis in SH-SY5Y Cells. Antioxidants (Basel). 2021, 10(12), 1962. ISBN or DOI: 10.3390/antiox10121962

27. Magurano F, Sucameli M, Picone P, Micucci M, Baggieri M, Marchi A, Bucci P, Gioacchini S, Catinella G, Borgonovo G, Dallavalle S, Nuzzo D, Pinto A. Antioxidant Activity of Citrus Limonoids and Investigation of Their Virucidal Potential against SARS-CoV-2 in Cellular Models. Antioxidants (Basel). 2021, 10(11), 1794. ISBN or DOI:  10.3390/antiox10111794

28. Fiorino S, Tateo F, Biase D, Gallo CG, Orlandi PE, Corazza I, Budriesi R, Micucci M, Visani M, Loggi E, Hong W, Pica R, Lari F, Zippi M. SARS-CoV-2: lessons from both the history of medicine and from the biological behavior of other well-known viruses. Future Microbiol. 2021, 16(14), 1105-1133. ISBN or DOI: 10.2217/fmb-2021-0064

29. Zippi M, Fiorino S, Budriesi R, Micucci M, Corazza I, Pica R, de Biase D, Gallo CG, Hong W. Paradoxical relationship between proton pump inhibitors and COVID-19: A systematic review and meta-analysis. World J Clin Cases. 2021, 9(12), 2763-2777. ISBN or DOI: 10.12998/wjcc.v9.i12.2763

30. Micucci M, Budriesi R, Aldini R, Fato R, Bergamini C, Vivarelli F, Canistro D, Bolchi C, Chiarini A, Rizzardi N, Pallavicini M, Frosini M, Angeletti A. Castanea sativa Mill. bark extract cardiovascular effects in a rat model of high-fat diet. Phytother Res. 2021, 35(4), 2145-2156. ISBN or DOI: 10.1002/ptr.6967

31. Mallamaci R, Budriesi R, Clodoveo ML, Biotti G, Micucci M, Ragusa A, Curci F, Muraglia M, Corbo F, Franchini C. Olive Tree in Circular Economy as a Source of Secondary Metabolites Active for Human and Animal Health Beyond Oxidative Stress and Inflammation. Molecules. 2021, 26(4), 1072. ISBN or DOI:  10.3390/molecules26041072

32. Carocci A, Roselli M, Budriesi R, Micucci M, Desaphy JF, Altamura C, Cavalluzzi MM, Toma M, Passeri GI, Milani G, Lovece A, Catalano A, Bruno C, De Palma A, Corbo F, Franchini C, Habtemariam S, Lentini G. Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities. ChemMedChem. 2021, 16(3), 578-588. ISBN or DOI: 10.1002/cmdc.202000692

33. Cavalluzzi MM, Budriesi R, De Salvia MA, Quintieri L, Piarulli M, Milani G, Gualdani R, Micucci M, Corazza I, Rosato A, Viale M, Caputo L, Franchini C, Lentini G. Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies. Pharmacol Rep. 2021, 73(1), 172-184. ISBN or DOI: 10.1007/s43440-020-00167-2

34. Zeka K, Marrazzo P, Micucci M, Ruparelia KC, Arroo RRJ, Macchiarelli G, Annarita Nottola S, Continenza MA, Chiarini A, Angeloni C, Hrelia S, Budriesi R. Activity of Antioxidants from Crocus sativus L. Petals: Potential Preventive Effects towards Cardiovascular System. Antioxidants (Basel). 2020, 9(11), 1102. ISBN or DOI:  10.3390/antiox9111102

35. Micucci M, Protti M, Aldini R, Frosini M, Corazza I, Marzetti C, Mattioli LB, Tocci G, Chiarini A, Mercolini L, Budriesi R. Thymus vulgaris L. Essential Oil Solid Formulation: Chemical Profile and Spasmolytic and Antimicrobial Effects. Biomolecules. 2020, 10(6), 860. ISBN or DOI: 10.3390/biom10060860

36. Chiaino E, Micucci M, Cosconati S, Novellino E, Budriesi R, Chiarini A, Frosini M. Olive Leaves and Hibiscus Flowers Extracts-Based Preparation Protect Brain from Oxidative Stress-Induced Injury. Antioxidants (Basel). 2020, 9(9), E806. ISBN or DOI: 10.3390/antiox9090806

37. Chiaino E, Micucci M, Durante M, Budriesi R, Gotti R, Marzetti C, Chiarini A, Frosini M. Apoptotic-Induced Effects of Acacia Catechu Willd. Extract in Human Colon Cancer Cells, Int J Mol Sci. 2020, 21(6), E2102. ISBN or DOI: 10.3390/ijms21062102

38. Micucci M, Viale M, Chiarini A, Spinelli D, Frosini M, Tavani C, Maccagno M, Bianchi L, Gangemi R, Budriesi R, 3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From Calcium-Channel Modulators Properties to Multidrug-Resistance Reverting Activity, Molecules. 2020, 25(5), 1056. ISBN or DOI:  10.3390/molecules25051056

39. Micucci M, Bolchi C, Budriesi R, Cevenini M, Maroni L, Capozza S, Chiarini A, Pallavicini M, Angeletti A, Antihypertensive phytocomplexes of proven efficacy and well-established use: Mode of action and individual characterization of the active constituents, Phytochemistry. 2020, 170, 112222. ISBN or DOI: 10.1016/j.phytochem.2019.112222

40. Farzaei MH, Singh AK, Kumar R, Croley CR, Pandey AK, Coy-Barrera E, Kumar Patra J, Das G, Kerry RG, Annunziata G, Tenore GC, Khan H, Micucci M, Budriesi R, Momtaz S, Nabavi SM, Bishayee A., Targeting Inflammation by Flavonoids: Novel Therapeutic Strategy for Metabolic Disorders, Int J Mol Sci. 2019, 20(19). ISBN or DOI: 10.3390/ijms20194957

41. Iaccarino N, Amato J, Pagano B, Di Porzio A, Micucci M, Bolelli L, Aldini R, Novellino E, Budriesi R, Randazzo A., Impact of phytosterols on liver and distal colon metabolome in experimental murine colitis model: an explorative study, J Enzyme Inhib Med Chem. 2019, 34(1), 1041-1050. ISBN or DOI: 10.1080/14756366.2019.1611802

42. Leoni A, Frosini M, Locatelli A, Micucci M, Carotenuto C, Durante M, Cosconati S, Budriesi R., 4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching, Eur J Med Chem. 2019, 169, 89-102. ISBN or DOI: 10.1016/j.ejmech.2019.02.075

43. Bisi A, Arribas RL, Micucci M, Budriesi R, Feoli A, Castellano S, Belluti F, Gobbi S, de Los Rios C, Rampa A., Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment, Eur J Med Chem. 2019, 163, 394-402. ISBN or DOI: 10.1016/j.ejmech.2018.12.003

44. Micucci M, Chiarini A., Budriesi R, Neutral/negative α1-AR antagonists and calcium channel blockers at comparison in functional tests on guinea-pig smooth muscle and myocardium, Pharmacol Rep. 2019, 71(1), 128-132. ISBN or DOI: 10.1016/j.pharep.2018.10.007

45. Bisi A, Micucci M, Gobbi S, Belluti F, Budriesi R, Rampa A., Cardiovascular Profile of Xanthone-Based 1,4 Dihydropyridines Bearing a Lidoflazine Pharmacophore Fragment, Molecules. 2018; 23 (12). ISBN or DOI: 10.3390/molecules23123088

46. Santulli C, Brizi C, Durante M, Micucci M, Budriesi R, Chiarini A, Frosini M, Apoptotic-induced effects of castanea sativa bark extract in human SH-SY5Y neuroblastoma cells. Natural Product Communications. 2018, 13, 887-890. ISBN or DOI:  10.1177/1934578X1801300726

47. Budriesi R, Vivarelli F, Canistro D, Aldini R, Babot Marquillas C, Corazza I, Fato R, Cirillo S, Bergamini C, D'Errico A, Bolchi C, Cevenini M, Degiovanni A, Frosini M, Camarda L, Chiarini A, Micucci M., Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats, PLoS One. 2018, 13(8), e0201540.  ISBN or DOI: 10.1371/journal.pone.0201540

48. Marangoni A, Foschi C, Micucci M, Nahui Palomino RA, Gallina Toschi T, Vitali B, Camarda L, Mandrioli M, De Giorgio M, Aldini R, Corazza I, Chiarini A, Cevenini R, Budriesi R. In vitro activity of Spirulina platensis water extract against different Candida species isolated from vulvo-vaginal candidiasis cases. PLoS One. 2017 Nov 30;12(11):e0188567.  ISBN or DOI: 10.1371/journal.pone.0188567

49. Leoni A, Budriesi R, Poli F, Lianza M, Graziadio A, Venturini A, Broccoli M, Micucci M. Ayurvedic preparation of Zingiber officinale Roscoe: effects on cardiac and on smooth muscle parameters, Nat Prod Res. 2017, 28, 1-8. ISBN or DOI:  10.1080/14786419.2017.1367779

50. Micucci M, Gotti R, Corazza I, Tocci G, Chiarini A, De Giorgio M, Camarda L, Frosini M, Marzetti C, Cevenini M, Budriesi R. Newer Insights into the Antidiarrheal Effects of Acacia catechu Willd. Extract in Guinea Pig, J Med Food. 2017, 20(6), 592-600. ISBN or DOI: 10.1089/jmf.2016.0154

51. Papa V, Ginocchietti L, Budriesi R, Micucci M, Costa R, Biondi R, Cevenini R, Chiarini A, Aldini R, Donati M, Pollini GM, Cenacchi G. In vitro activity of a partially purified and characterized bark extract of Castanea sativa Mill. (ENC®) against Chlamydia spp, Ultrastructural Pathology. 2017, 1–7. ISBN or DOI: 10.1080/01913123.2016.1275909

52. Santulli C, Brizi C, Micucci M, Del Genio A, De Cristofaro A, Bracco F, Pepe GL, di Perna I, Budriesi R, Chiarini A, Frosini M. Castanea sativa Mill. Bark Extract Protects U-373 MG Cells and Rat Brain Slices Against Ischemia and Reperfusion Injury, J Cell Biochem. 2017, 118(4), 839-850. ISBN or DOI: 10.1002/jcb.25760

53. Roselli M, Carocci A, Budriesi R, Micucci M, Toma M, Di Cesare Mannelli L, Lovece A, CatalanoA, Cavalluzzi MM, Bruno C, De Palma A, Contino M, Perrone MG, Colabufo NA, Chiarini A, Franchini C, Ghelardini C, Habtemariam S, Lentini G. Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues, Eur J Med Chem. 2016, 121, 300-7. ISBN or DOI: 10.1016/j.ejmech.2016.05.046

54. Micucci M, Angeletti A, Cont M, Corazza I, Aldini R, Donadio E, Chiarini A, Budriesi R. Hibiscus Sabdariffa L. Flowers and Olea Europea L. Leaves Extract-Based Formulation for Hypertension Care: In Vitro Efficacy and Toxicological Profile, J Med Food.  2016, 19(5), 504-12. ISBN or DOI: 10.1089/jmf.2015.0072

55. Carosati E, Cosimelli B, Ioan P, Severi E, Katneni K, Chiu FC, Saponara S, Fusi F, Frosini M, Matucci R, Micucci M, Chiarini A, Spinelli D, Budriesi R. Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism, J Med Chem. 2016, 59(7), 3340-52. ISBN or DOI:  10.1021/acs.jmedchem.6b00030

56. Brizi C, Santulli C, Micucci M, Budriesi R, Chiarini A, Aldinucci C, Frosini M. Neuroprotective effects of Castanea sativa Mill. bark extract in human neuroblastoma cells subjected to oxidative stress, J Cell Biochem. 2016, 117(2), 510-20. ISBN or DOI:  10.1002/jcb.25302

57. Micucci M, Malaguti M, Gallina Toschi T, Di Lecce G, Aldini R, Angeletti A, Chiarini A, Budriesi R, Hrelia S. Cardiac and Vascular Synergic Protective Effect of Olea europea L. Leaves and Hibiscus sabdariffa L. Flower Extracts, Oxid Med Cell Longev. 2015, 2015, 318125. ISBN or DOI: 10.1155/2015/318125

58. Spinelli D, Budriesi R, Cosimelli B, Severi E, Micucci M, Baroni M, Fusi F, Ioan P, Cross S,   Frosini M, Saponara S, Matucci R, Rosano C, Viale M, Chiarini A, Carosati E. Playing with opening and closing of heterocycles: using the cusmano-ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and p-glycoprotein inhibitors, Molecules. 2014, 19(10), 16543-72. ISBN or DOI: 10.3390/molecules191016543

59. Aldini R, Micucci M, Cevenini M, Fato R, Bergamini C, Nanni C, Cont M, Camborata C, Spinozzi S, Montagnani M, Roda G, D'Errico-Grigioni A, Rosini F, Roda A, Mazzella G, Chiarini A, Budriesi R. Antiinflammatory effect of phytosterols in experimental murine colitis model: prevention, induction, remission study, PLoS One. 2014, 9(9), e108112. ISBN or DOI: 10.1371/journal.pone.0108112

60. Arroo RRJ, Beresford K, Bhambra AS, Boarder M, Budriesi R, Cheng Z, Micucci M, Ruparelia KC, Surichan S, Androutsopoulos VP. Phytoestrogens as natural prodrugs in cancer prevention: Towards a mechanistic model, Phytochemistry Reviews. 2014, 1-14. ISBN or DOI: 10.1007/s11101-014-9355-3

61. Micucci M, Ioan P, Aldini R, Cevenini M, Alvisi V, Ruffilli C, Chiarini A, Budriesi R. Castanea sativa Mill. Extract Contracts Gallbladder and Relaxes Sphincter of Oddi in Guinea Pig: A Natural Approach to Biliary Tract Motility Disorders, J Med Food. 2014, 17(7), 795-803. ISBN or DOI: 10.1089/jmf.2013.0090

62. Micucci M, Aldini R, Cevenini M, Colliva C, Spinozzi S, Roda G, Montagnani M, Camborata C, Camarda L, Chiarini A, Mazzella G, Budriesi R. Curcuma longa L. as a therapeutic agent in intestinal motility disorders. 2: Safety profile in mouse, PLoS One. 2013, 8(11): e80925. ISBN or DOI: 10.1371/journal.pone.0080925

63. Fumagalli L, Pallavicini M, Budriesi R, Bolchi C, Canovi M, Chiarini A, Chiodini G, Gobbi M, Laurino P, Micucci M, Straniero V, Valoti E. 6-Methoxy-7-benzofuranoxy and 6-methoxy-7-indolyloxy analogues of 2-[2-(2,6-dimethoxyphenoxy)ethyl]aminomethyl-1,4-benzodioxane (WB4101): discovery of a potent and selective α-adrenoceptor antagonist, J Med Chem. 2013, 56(16), 6402-12. ISBN or DOI: 10.1021/jm400867d

64. Catalano A, Budriesi R, Bruno C, Di Mola A, Defrenza I, Cavalluzzi M M, Micucci M, Carocci A, Franchini C, Lentini G. Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers, Eur J Med Chem. 2013, 18, 65C, 511-516. ISBN or DOI: 10.1016/j.ejmech.2013.05.008.

65. Locatelli A, Cosconati S, Micucci M, Leoni A, Marinelli L, Bedini A, Ioan P, Spampinato SM, Novellino E, Chiarini A, Budriesi R. Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity, J Med Chem. 2013, 56(10), 3866-77. ISBN or DOI: 10.1021/jm301839q

66. Chiarini A, Micucci M, Malaguti M, Budriesi R, Ioan P, Lenzi M, Fimognari C, Gallina Toschi T, Comandini P, Hrelia S. Sweet Chestnut (Castanea Sativa Mill.) bark extract: cardiovascular activity and myocyte protection against oxidative damage, Oxid Med Cell Longev. 2013, 2013; 2013:471790. ISBN or DOI: 10.1155/2013/471790

67. Fumagalli L, Pallavicini M, Budriesi R, Gobbi M., Straniero V, Zagami M, Chiodini G, Bolchi C, Chiarini A, Micucci M, Valoti E. Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective alpha 1B-adrenoceptor antagonist, Eur J Med Chem. 2012, 58, 184-191. ISBN or DOI: 10.1016/j.ejmech.2012.09.049

68. Aldini R, Budriesi R, Roda G, Micucci M, Ioan P, D’Errico-Grigioni A, Sartini A, Guidetti E, Marocchi M, Cevenini M, Rosini F, Montagnani M, Chiarini A, Mazzella G. Effect of Curcuma longa extract on the intestinal motility in acute and chronic DSS induced colitis in mice, Plose One. 2012, 7, e44650, pp12. ISBN or DOI: 10.1371/journal.pone.0044650

69. Carosati E, Ioan P, Micucci M, Broccatelli F, Cruciani G, Zhorov BS, Chiarini A, Budriesi R. 1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story so Far And Perspectives. (Part 2): Action in Other Targets and Antitargets, Curr Med Chem. 2012, 19, 4306-4323. ISBN or DOI: 10.2174/092986712802884204

70. Ioan P, Carosati E, Micucci M, Cruciani G, Broccatelli F, Zhorov BS, Chiarini A, Budriesi R. 1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story so Far And Perspectives. (Part 1): Action in Ion Channels and GPCRs., Curr Med Chem. 2011, 18, 4901-4922. ISBN or DOI: 10.2174/092986711797535173

71. Cosimelli B, Severi E, Novellino E, Cavaccini A, Cataldi M, Budriesi R, Micucci M, Chiarini A, Ioan P. Preliminary Finding on a New Calcium Channel Entry Blocker Chemotype: 5,6-Diamino-4-hydroxy-2-mercaptopyrimidine Derivatives, J Med Chem. 2011, 54, 5597-5601. ISBN or DOI: 10.1021/jm200414s

72. Budriesi R, Ioan P, Leoni A, Pedemonte N, Locatelli A, Micucci M, Chiarini A, L. J. Galietta. Cystic Fibrosis: a New Target for 4-Imidazo[2,1-b]thiazole-1,4- Dihydropyridines, J Med Chem. 2011, 54, 3885-3094. ISBN or DOI: 10.1021/jm200199r

73. Tasso B, Budriesi R, Vazzana I, Ioan P, Micucci M, Novelli F, Tonelli M, Sparatore A, Chiarini A, Sparatore F. Novel Quinolizidinyl Derivatives as Antiarrhythmic Agents: 2. Further Investigation, J Med Chem. 2010, 53, 4668-4677. ISBN or DOI: 10.1021/jm100298d

74. Budriesi R, Ioan P, Micucci M, Micucci E, Limongelli V, Chiarini A. Stop Fitan: antispasmodic effect of natural extract of chestnut wood in guinea pig ileum and proximal colon smooth muscle. J Med Food. 2010 Oct;13(5):1104-10. ISBN or DOI: 10.1089/jmf.2009.0210

Ho redatto una parte del libro “La Chimica e gli alimenti- nutrient e aspetti nutraceutici” Casa Editrice Ambrosiana. Distribuzione esclusiva Zanichelli, 2019

Ho scritto il libro "Ipertensione e aterosclerosi - il nuovo paradigma della Nutraceutica", 2021