MOLECULAR MECHANISM OF METABOLIC DISEASES
MECCANISMI MOLECOLARI DELLE MALATTIE METABOLICHE
| A.Y. | Credits |
|---|---|
| 2015/2016 | 9 |
| Lecturer | Office hours for students | |
|---|---|---|
| Luciana Vallorani | on appointment by calling 0722303419 |
Assigned to the Degree Course
| Date | Time | Classroom / Location |
|---|
Learning Objectives
The course will provide the molecular basis of diseases that most frequently affect the adult population of the industrialized societies . It will also provide guidance regarding prevention of such diseases through appropriate physical activity and healthy eating habits.
Program
Elements of environmental disease.
Mechanisms of cellular damage. Cell death: apoptosis and necrosis. Innate immunity: cells, receptors and mechanisms of action.
Acute and chronic inflammation, chemical mediators of inflammation, systemic manifestations of inflammation.
Acquired immunity: lymphocytes and cellular basis of adaptive immunity, B cells and antibodies, the generation of antibody diversity. T cells and MHC proteins.
Relations between metabolic organs in various nutritional and hormonal states .
Diabetes mellitus: diabetes type 1 and 2; Insulin: structure, function and mechanism of action; Biochemical alterations of the tissues resulting hyperglycemia.
Obesity: white and brown adipose tissue;
biochemical composition of adipocyte; Termogenesis, Adipose tissue as secretory organ.
Synthesis, structure and function of LDL and HDL.
Atherosclerosis as chronic inflammatory response
Metabolic syndrome
Osteoporosis: bone biochemical composition; relations with calcium, estrogen and physical activity.
Cancer: Molecular basis of the behavior of neoplastic cells
Bridging Courses
none
Learning Achievements (Dublin Descriptors)
Students have to prove the acquirement of the basic knowledge of defensive mechanisms put in place by human organism in response to harmful stimuli of various nature. Students have to prove the understanding of the concepts and have the ability to transfer such acquisitions in practice of patients's rehabilitation.It must show the possession of communication skills , using a correct terminology and they must be able to interface with other professional figures working in healthcare. Students must show the possession of the ability to use knowledges and concepts in the programming of customized programs for functional rehabilitation of patients affected by different clinical conditions.
Teaching Material
The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it
Teaching, Attendance, Course Books and Assessment
- Teaching
front lessons
- Attendance
no
- Course books
Patologia generale Pontieri , Russo, Frati Ed. Piccin Nuova Libraria 2010
Immunologia Coico, Sunshine and Benjamini Edises 2005
Other additional material will be available in the platform moodle
- Assessment
Oral examination
- Disability and Specific Learning Disorders (SLD)
Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.
To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.
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