The purpose of this course is to supply theoretical and practical mastery and competence, necessary for the basic operations in the qualitative and quantitative analysis of   pharmaceuticals and toxic substances.

Theoretical basis.

-Rules of security in the laboratories. Organisation. Equipments and instrumentation. Behavior.

-Basic techniques and operations: solubility, dilution, concentration; precipitation, settling, filtration, centrifugation,  extraction.

-Analyses of inorganic ions of pharmaceutical and toxicological interest.

-Chromatographic techniques; notes concerning the separation mechanisms; adsorption,  partition,  exclusion, affinity,  ion-exchange.

-Planar chromatography, paper chromatography, thin layer chromatography.

-Acid-base titrations in aqueous and non aqueous solutions; complexometric, red-ox and   gravimetric titrations.

-Treatment of analytical data and application to the drug analysis.

Practical exercises.

-Separation and identification of cations and anions of pharmaceutical and toxicological interest. Analytical determinations by FU assays.

-TLC and HPTLC applications.

-Preparation of solutions and dilution.

-Quantitative analysis performed by titrations.

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

Teaching

Oral lectures and laboratories.

Attendance

The frequency of laboratory is compulsory.

Course books

 

Reference books:

-P.Barbetti, M.G.Quaglia, L’analisi qualitativa nella chimica farmaceutica e tossicologica, Galeno Editore.

 

-G.C.Porretta, Analisi di preparazioni farmaceutiche. Analisi quantitativa, CISU Editore.

or

– E.Abignente, D.Melisi, M.G.Rimoli, Principi di Analisi Quantitativa dei medicinali, Ed. Loghìa.

 

In consultation:

-Farmacopea Ufficiale Italiana ed Europea.

-H.H.Bauer, G.D.Christian, J.E.O’Really, Analisi strumentale, Piccin Editore.

-L.F.Hamilton, S.G.Simpson, D.W.Ellis, Calcoli stechiometrici e problemi di chimica analitica, Piccin Editore.

 

Assessment

Oral examination.

Disability and Specific Learning Disorders (SLD)

Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.