The final aim of the course is to link basic science with the fundamental pathogenetic and pathophysiological mechanisms underlying disease.

1. Cell injury, cell death and adaptations; 2. Inflammation and repair; 3. Hemodynamic Disorders, Thromboembolism and Shock; 4. Diseases of the immune system; 5. Neoplasia; 6. Genetic Disorders; 7. Environmental and Nutritional Diseases 8. Blood vessels: structure and function of blood vessels; 9. Diabetes Mellitus.

Biochemistry. General Physiology.

D1- KNOWLEDGE AND UNDERSTANDING

The students have to demonstrate that they have acquired the knowledge regarding the mechanisms responsible for the development of human diseases: the causes of cell/tissue damage and death; fundamental pathogenetic mechanisms associated with immunity, inflammation and carcinogenesis; inheritance of genetic pathologies. These skills will be assessed through the final exam.

D2-APPLYING KNOWLEDGE AND UNDERSTANDING

The student should be able to use the principles of general pathology to understand the pathogenetic mechanisms. In particular, he/she will have to use these principles during his profession in the health sector or in experimental research. These skills will be assessed through the final exam.

D3-MAKING JUDGEMENTS

The students have to acquire knowledge such as to allow the recognition of the mechanisms responsible for the development of a disease and to identify specific pathological conditions with application in the prevention, diagnosis and therapy of diseases. These skills will be tested both with the written test and through targeted oral questions. These skills will be assessed through the final exam.

D4-COMMUNICATION SKILLS

The student must be able to describe the principles and concepts learned during the course expressing themselves clearly, with appropriate terms and with appropriate examples. This ability will be assessed during the oral examination.

D5-LIFELONG LEARNING SKILLS

The students should be able to construct his/her scientific lifelong learning skills in a critical and autonomous way, being able to properly use the teaching material provided by the teacher and the in-depth own material. These skills, as far as possible, will be stimulated by the teacher by proposing insights which will then be explained and discussed during the lessons.

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

Supporting activities are not provided.

Teaching

Lectures.

Attendance

The basic knowledge and skills that students should have in order to properly carry out the activities included in the course are related to anatomy, biochemistry and physiology.

Course books

The topics listed in the syllabus can be studied in one of the following books:

- Robbins Basic pathology, Kumar V., Abbas A.K., Fausto N., Aster J.C., Masson (Ninth Edition).

- Rubin R., Strayer D.S., Patologia generale (Patologia d'organo e molecolare), PICCIN.
- Majno G., Joris I., Cellule, tessuti e malattia, principi di patologia generale, Casa Editrice Ambrosiana.
- Pontieri G.M., Russo M.A., Frati L. Patologia generale (Tomo I), Piccin Editore.

Consulation book:

- Strayer D.S., Rubin E., Patologia generale - Anatomia patologica, PICCIN (II edizione).

Assessment

The assessment, which has the purpose of ascertaining the acquisition of the knowledge and skills expected, takes place through the final exam only, which consists of a written test and an oral test.

The written test consists in solving a multiple-choice test as it intends to evaluate the basic knowledge related to the main mechanisms responsible for the development of pathologies. The evaluation of the written test is formulated by a positive result if the mark is sufficient. The duration of the written test is 2 hours.

The final assessment, which takes into account the results of the written and oral tests, is given out of thirty and reflects the overall evaluation of the candidate.

Disability and Specific Learning Disorders (SLD)

Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.

Attendance

The basic knowledge and skills that students should have in order to properly carry out the activities included in the course are related to anatomy, biochemistry and physiology.

Course books

The topics listed in the syllabus can be studied in one of the following books:

- Robbins Basic pathology, Kumar V., Abbas A.K., Fausto N., Aster J.C., Masson (Ninth Edition).

- Rubin R., Strayer D.S., Patologia generale (Patologia d'organo e molecolare), PICCIN.
- Majno G., Joris I., Cellule, tessuti e malattia, principi di patologia generale, Casa Editrice Ambrosiana.
- Pontieri G.M., Russo M.A., Frati L. Patologia generale (Tomo I), Piccin Editore.

Consultation book:

- Strayer D.S., Rubin E., Patologia generale - Anatomia patologica, PICCIN (II edizione).

Assessment

The assessment, which has the purpose of ascertaining the acquisition of the knowledge and skills expected, takes place through the final exam only, which consists of a written test and an oral test.

The written test consists in solving a multiple-choice test as it intends to evaluate the basic knowledge related to the main mechanisms responsible for the development of pathologies. The evaluation of the written test is formulated by a positive result if the mark is sufficient. The duration of the written test is 2 hours.

The final assessment, which takes into account the results of the written and oral tests, is given out of thirty and reflects the overall evaluation of the candidate.

Disability and Specific Learning Disorders (SLD)

Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.