The course aims to provide the fundamental knowledge of theoretical and applied Virology. The principal learning objectives will focus on: 1) the structure and classification of viral particles; 2) the mechanisms responsible for viral replication; 3) the techniques for virus study; 4) antiviral drugs and methods for the prevention of viral disease (vaccines); 5) the mechanisms that underlies the interactions between viruses and higher organisms.

·     Introduction to and history of Virology

·     Structure and classification of Eukaryotic viruses

·     Virus replication and effects on their cellular hosts

·     Virus genetics. Virus titration, cultivation and isolation methodologies

·     Bacteriophages

·     Characteristics of some virus families: Herpersviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae, Hepadnaviridae, Flaviviridae, Retroviridae.

·     Introduction to antiviral therapy and vaccines

Knowledge and understanding ability: Students must be able to describe the properties of viruses, highlighting the differences and similarities with Eukaryotic and Prokaryotic cells. Students will have to know the mechanisms underlying viral replication and will have to be familiar with the main methods applied to the control of viral growth. It will be important to acquire knowledge on antiviral drugs and on methods for the prevention of viral disease (vaccines). Basic knowledge on the mechanisms that drive the interactions between viruses and higher organisms is also required.

Ability to apply knowledge and understanding: Both during oral and written exams, students will have to clearly and correctly illustrate the topics that they have studied, using the correct scientific and microbiological terminology.

Independent judgment: Students will have to be able to critically apply the acquired knowledge to solve questions concerning Virology.

Communicative ability: Students will have to be able to use the microbiological language and to link the different microbiological features with appropriate examples.

Learning capability: Student must demonstrate to have acquired the ability to illustrate and discuss with people of equal preparation and expertise on Microbiology-related topics.

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

Laboratory activities and seminars will be offered to attending students

Attendance

Lectures

Course books

·  Dehò, G. e Galli, E. Biologia dei microrganismi. Casa Editrice Ambrosiana.

·  Antonelli, Clementi. Principi di Virologia Medica. Casa Editrice Ambrosiana.

·  Dimmock, Easton, Leppard. Introduzione alla Virologia Moderna. Casa Editrice Ambrosiana.

Assessment

The final assessment consists of a written and an oral exam.

The exam is aimed at verifying the level of knowledge and comprehension of the topics of the program and the reasoning skills developed by the student.

The written test includes both open and closed questions on the topics covered during lectures and laboratory exercises. Open questions are evaluated for accuracy, completeness of content as well as synthesis and elaboration skills. Property of language, clarity of exposition, acquired knowledge and ability to make connections between the different topics are evaluated during the oral examination. Overall, the exam aims to verify the achievement of the objectives in terms of knowledge and comprehension of the topics, as well as communication skills. The evaluation is expressed in thirtieths (minimum mark 18/30, maximum mark 30/30 cum laude).

Disability and Specific Learning Disorders (SLD)

Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.