MICROBIOLOGY
MICROBIOLOGIA
A.Y. | Credits |
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2022/2023 | 6 |
Lecturer | Office hours for students | |
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Barbara Citterio | Every day by appointment by email (barbara.citterio@uniurb.it) |
Teaching in foreign languages |
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Course with optional materials in a foreign language
English
This course is entirely taught in Italian. Study materials can be provided in the foreign language and the final exam can be taken in the foreign language. |
Assigned to the Degree Course
Date | Time | Classroom / Location |
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Date | Time | Classroom / Location |
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Learning Objectives
The course is aimed at acquiring the theoretical and applicative principles of general microbiology. The primary objective of the course is the acquisition of knowledge on the taxonomy, morphology, physiology and genetics of microorganisms. These notions will be applied to deepen the understanding of the molecular and cellular interactions that microorganisms establish between themselves and with the environment. Particular attention will be paid to the knowledge of the cellular and molecular bases of microbial virulence and pathogenicity, of the problem of antibiotic resistance and on new types of vaccines.
Program
Bacteria
Structure of the prokaryotic cell:
-General characteristics, microscopic study, shapes and disposal;
-Architecture of the bacterial cell genetic material, cytoplasm, cytoplasmic membrane, cell wall peptidoglycan and organization of the cell wall in Gram +, Gram- and acid-resistant capsule, pili, flagella
Reproduction of bacteria:
-Cell division, bacterial spore, VBNC.
Cultivation of bacteria:
-Nutritional requirements of microorganisms, culture media, bacterial growth, growth curve of bacteria, cultivation techniques.
Bacterial metabolism:
-Energy and enzymes
-Energy metabolism: bacterial fermentation, aerobic and anaerobic respiration, phosphorylation, macromolecular synthesis (DNA, RNA, proteins, peptidoglycan).
Bacterial genetics:
-Bacterial chromosome
-Plasmids and antibiotic resistance.
-Mutations and their chemical bases
-Genetic recombinations (transformation, translation, conjugation)
Bacterial Pathogenesis:
-Mechanisms of host colonization;
-Deep-tissue penetration of the host organism
-Evasion mechanisms of host defense
-Virulence factors: flagella, capsule, fimbriae, peptidoglycan, teichoic acids, outer membrane proteins, enzymes, bacterial exotoxins, lipopolysaccharide (endotoxin).
Antibiotic resistance:
Mechanisms and spread
Bacteriphages
Structure
General characteristics of fungi of medical interest
Basics of Immunology:
-the antigens
-the constitutive defenses against infection (professional phagocytes, phagocytosis, complement, interferon)
-the inducible defenses against infection (the humoral immune response, the cell-mediated immune response)
Vaccines
Bridging Courses
Overcoming Human Anatomy with Element of Animal Biology exam
Learning Achievements (Dublin Descriptors)
D1-Knowledge and understanding ability: Knowledge of the microbial importance and role especially for the human health. Understanding the specific words and language of this discipline
D2-Ability to apply knowledge and understanding: Understanding the microbiology importance as biological subject to study and understand the morphological, metabolic and genetic features of microorganisms
D3-Independent judgment: Understanding the bacteria importance as simplified models to study more complex organisms
D4-Communicative ability: Capability of using the microbiological language and of linking the different microbiological feaures.
D5-Learning capability:
The student must demonstrate that he / she is able to:
- maintain a contradiction with people of equal preparation and expertise in different themes, regulatory, scientific and procedural;
-illustrate and discuss in groups strategies for evaluating the interaction man-organism.
Teaching Material
The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it
Supporting Activities
Possible seminars agreed upon with students
Teaching, Attendance, Course Books and Assessment
- Teaching
Frontal lectures
- Attendance
No attendance
- Course books
G. Dehò, E. Galli, Biologia dei microrganismi, Ed. Ambrosiana
- Assessment
The final assessment will be by oral interview consisting of questions on at least 3 topics discussed in the course. The purpose of the test is to verify the acquired knowledge and to evaluate the ability to correlate the various topics discussed in the course (descriptors 1 and 2), communication skills (descriptor 4) and the ability to solve practical problems (descriptors 3 and 5). Responses will be judged on the basis of the knowledge of the subject, the display capacity and the language used as the correct and appropriate scientific terminology.
- Disability and Specific Learning Disorders (SLD)
Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.
To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.
Additional Information for Non-Attending Students
- Attendance
No attendance
- Course books
G. Dehò, E. Galli, Biologia dei microrganismi, Ed Ambrosiana
- Assessment
The final assessment will be by oral interview consisting of questions on at least 3 topics discussed in the course. The purpose of the test is to verify the acquired knowledge and to evaluate the ability to correlate the various topics discussed in the course (descriptors 1 and 2), communication skills (descriptor 4) and the ability to solve practical problems (descriptors 3 and 5). Responses will be judged on the basis of the knowledge of the subject, the display capacity and the language used as the correct and appropriate scientific terminology.
- Disability and Specific Learning Disorders (SLD)
Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.
To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.
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