The main objective of the course is to provide knowledge about innovative pharmaceutical systems aimed at the delivery of drugs. Basic knowledge relating to the design and optimization of drug delivery systems will also be provided through the quality by design approach.

1. Physico-chemical and biopharmaceutical principles underlying the design of dosage forms

2. Excipients for the formulation of drug delivery systems

3. Drug release control mechanisms

4. Main delivery technologies: a) polymer conjugates, b) liposomes, c) nanoparticles and microparticles, d) micro / nanomechanical devices.

5. Routes of administration for drugs: a) parenteral, b) ophthalmic, c) transdermal, d) intravaginal and intravesical, e) nasal, f) subcutaneous, g) oral.

6. Quality by design (QbD) and Design of Experiment (DOE) in the development of drug delivery systems

Not provided

D1 - KNOWLEDGE AND UNDERSTANDING. At the end of the course, the student will have to demonstrate to be able to know the systems and approaches used for the controlled administration of biological drugs.

D2 - ABILITY TO APPLY KNOWLEDGE AND UNDERSTANDING. At the end of the course, the student will have to demonstrate the ability to classify and describe the various innovative technologies for the design of active ingredient delivery systems and to recognize the different mechanisms and kinetics underlying the release.

D3 - AUTONOMY OF JUDGMENT. At the end of the course the student will have to demonstrate the ability to design and characterize controlled release systems of active ingredients, based on the chemical-physical properties of the materials used and appropriate formulation methodologies.

D4 - COMMUNICATION SKILLS. . At the end of the course, the student must demonstrate that he can communicate and transmit the concepts and notions learned during the training activity with appropriate terms and examples.

D5 - LEARNING SKILLS. At the end of the course the students will have to demonstrate that he is able to find and apply new information, compared to that provided during the training activity, necessary to understand and address the problems underlying the design and optimization of the drug delivery systems.

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

Teaching

Lectures in the classroom carried out in a traditional way assisted by the projection of didactic material. The teaching material consists of topics from the recommended books and selected scientific publications.

Innovative teaching methods

The face-to-face teaching method will be enriched with individual and group exercises and insights based on Student-centered learning, Flipped classrooms, and Focus group.

Attendance

Attendance to classes is not mandatory but is strongly recommended on a regular basis to encourage both classroom interaction and the acquisition of knowledge and skills.

Course books

• Aulton M.E. -  Tecnologie farmaceutiche - Progettazione e allestimento dei medicinali - EDRA
• Colombo P. - Principi di tecnologia farmaceutica - CEA Edizioni
• Perrie Y. and Rades T. - Pharmaceutics: Drug Delivery and Targeting - Pharmaceutical Press

Assessment

The exam consists of a written test (unless otherwise indicated related to the health emergency) followed by an oral test.

The written test, lasting 2 hours, is divided into 4 open-ended questions and will be assessed with a mark expressed out of thirty. For admission to the oral test, the student must have acquired a score of 18/30 in the written test.

Disability and Specific Learning Disorders (SLD)

Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.

Teaching

Non-attending students can use the Moodle platform (Blended Learning UniUrb-CISDEL)

Attendance

Attendance to the lectures is not mandatory but is strongly recommended on a regular basis to encourage both classroom interaction and the acquisition of knowledge and skills.

Course books

• Aulton M.E. -  Tecnologie farmaceutiche - Progettazione e allestimento dei medicinali - EDRA
• Colombo P. - Principi di tecnologia farmaceutica - CEA Edizioni
• Perrie Y. and Rades T. - Pharmaceutics: Drug Delivery and Targeting - Pharmaceutical Press

Assessment

The exam consists of a written test (unless otherwise indicated related to the health emergency) followed by an oral test.

The written test, lasting 2 hours, is divided into 4 open-ended questions and will be assessed with a mark expressed out of thirty. For admission to the oral test, the student must have acquired a score of 18/30 in the written test.

Disability and Specific Learning Disorders (SLD)

Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.