The aim of the course is to provide the student with concepts about the molecular basis, development, mechanism of action and therapeutic application of common classes of drugs.

Specifically, the aims of the course are the knowledge of:

- Molecular basis  and mechanism of action of the indicated drugs

- Side effects and therapeutic applications of indicated drugs.

Farmaci chemioterapici ad azione antibatterica e antivirale. Farmacologia della trasmissione adrenergica e colinergica. Farmaci che modulano la trasmissione neuromuscolare e gangliare. Farmaci della trasmissione serotoninergica. Neurotrasmissione aminoacidergica e sua modulazione farmacologica. Anestetici generali e locali. Antipsicotici. Antidepressivi. Farmaci antimaniacali. Ansiolitici e ipnotici. Antiepilettici. Farmaci utilizzati nel trattamento delle patologie neurodegenerative. Miorilassanti. Analgesici e oppiodi. Farmaci antinfiammatori e DMARDs. Terapia antipertensiva. Farmacologia dello scompenso cardiaco e dell'angina pectoris. Farmaci antiaggreganti piastrinici, antianticoagulanti e fibrinolitici. Fattori emopoietici. Farmaci antiobesità. Farmaci antidislipidemici. Antistaminici. Basi farmacologiche della terapia antiasmatica ed antiallergica. Basi farmacologiche della terapia immunomodulante. Diuretici. Farmaci dell'apparato digerente. Farmacologia del diabete di tipo I e II. Farmaci attivi nelle patologie ossee.

General and molecular Biochemistry

Pharmacology and Pharmacotherapy I

Pathology

At the end of the course, the student will have built a knowledge of the main classes of drugs, their therapeutic uses, and the related toxic effects.

Knowledge and Understanding: The students will achieve the molecular basis, the pharmacology (i.e. pharmacokinetics and pharmacodynamics), and side effects of drugs.

Ability to apply knowledge and understanding: The students will acquire a  proper pharmacological language and will be able to apply the acquired principles of  drug's activity for the study of intracellular signaling.

Judgment: The student will be able to critically evaluate the pro and cons of biotechnological drugs.

Communication skills: The student will be able to describe the pharmacology of Biotech drugs with proper scientific language.

Learning skills: The student will be able to build up his scientific knowledge in a critical way, using not only the study material provided by the professor but also dedicating himself to in-depth studies.

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

Supporting activities are not scheduled.

Teaching

 Lectures (presentations in MS Power Point, scientific papers etc,).

Innovative teaching methods

Scientific papers for  an update on innovative drugs

Attendance

Knowledge of Pharmacology and Pharmacotherapy, Biochemistry and Patology.

Course books

Goodman and Gilman - Le basi farmacologiche della terapia (2019)

Assessment

During the course, there will be two in itinere written tests which replace the final exam. In this case, the final outcome will be the mean of the two marks achieved in each test, only if both are ≥ 18/30. Those who do not achieve a mark ≥ 18 in one of the two partial tests must take the full examination. 

The written test consists of a series of multiple-choice and open questions. The time available is of three hours.

Students who have passed both tests, but are not satisfied with the result, can refuse by communicating it within 5 days from the date of publication of the result. In that case, they have to register for the regular exam.

The exam consists of an oral test. The candidate will be asked questions on topics covered during the lessons in order to ascertain that the student has acquired the basic concepts on the development, mechanism of action, side effects and therapeutics of drugs. The final mark, expressed out of thirty, will result from the candidate's ability to answer the questions asked in an exhaustive and reasoned manner and with an appropriate scientific language.

Disability and Specific Learning Disorders (SLD)

Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.

Attendance

The same of attending students.

Course books

The same of attending students.

Assessment

The exam consists of an oral test. The candidate will be asked questions on topics covered during the lessons in order to ascertain that the student has acquired the basic concepts on the pharmacology of common drugs classes. The final mark, expressed out of thirty, will result from the candidate's ability to answer the questions asked in an exhaustive and reasoned manner and with appropriate scientific language.

Disability and Specific Learning Disorders (SLD)

Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.