Università degli Studi di Urbino Carlo Bo / Portale Web di Ateneo


A.Y. Credits
2019/2020 6
Lecturer Email Office hours for students
Donatella Desideri The professor will receive the students by previous e mail appointment
Teaching in foreign languages
Course with optional materials in a foreign language English
This course is entirely taught in Italian. Study materials can be provided in the foreign language and the final exam can be taken in the foreign language.

Assigned to the Degree Course

Pharmaceutical Chemistry and Technology (LM-13)
Date Time Classroom / Location
Date Time Classroom / Location

Learning Objectives

The aim of the course is to provide basic knowledge on preparation and quality control of radiopharmaceuticals used for diagnosis and therapy in nuclear medicine in accordance with regulations for clinical activity and for clinical trials. Second objective is to let the student know the figure of the radiopharmacist, providing the basic knowledge on the activity of this figure in the hospital setting.


Principles of radiation physics: structure of the atom, the stable and unstable nucleus, the radioactive decay and decay general equation, half life, specific activity. Interaction of radiation with matter, penetrating and non penetrating radiation.
Dosimetry: absorbed dose, equivalent dose and effective dose, biologic effects of ionization radiation.
Radiopharmaceuticals in nuclear medicine: generality
Radiopharmaceuticals for diagnostic in nuclear medicine: scintillation imaging, SPET and PET, general properties of radiopharmaceuticals for diagnostic, gamma and positron emitter radiopharmaceuticals.
Radioterapy: methods, radiopharmaceuticals for metabolic radioterapy.
Evaluation of the risk of adverse reactions.
Production of radionuclides for radiopharmaceuticals.
Quality control and Quality Assurance.

Regulatory requirements.

Bridging Courses

Highly recommended having passed the exam of Pharmaceutical and Toxicological Chemistry 1 to acquire the knowledge / skills necessary for a better understanding of the course.

Learning Achievements (Dublin Descriptors)

At the end of course the student will have to show:

A) to know the fundamental principles of radiation physics and effects of radiation; the main radiopharmaceuticals in nuclear medicine for diagnosis and therapy;the main adverse reactions; basic knowledge on preparation and quality control of radiopharmaceuticals used for diagnosis and therapy in nuclear medicine; the main regulatory issues
B) to have acquired applicative skills concerning the preparation and quality control of radiopharmaceuticals in accordance with regulations for clinical activity and for clinical trials
C) to be able to assess and solve problems autonomously related to the course content
D) to have developed oral and written communication skills suited to the presentation of the concepts acquired
E) to be able to explore the topics in different contexts and autonomously

Teaching Material

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

Didactics, Attendance, Course Books and Assessment


Theoretical lectures

Course books

Lecture notes and slides of the course


The aim of the examination is to verify the level of achievement of the previously indicated educational objectives. The student will be evaluated  on the demonstrated ability to expose the topics in a concise, complete and correct way.
The exam consists of a written test with 15 open-ended questions lasting one hour. The evaluation criterion for the questions is as follows: 2 point for each correct answer; to pass the exam it is necessary to acquire a minimum score of 18 out of 30.

« back Last update: 04/09/2019


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