BIOCHEMISTRY
BIOCHIMICA
| A.Y. | Credits |
|---|---|
| 2022/2023 | 8 |
| Lecturer | Office hours for students | |
|---|---|---|
| Roberto Campagna | Tuesday 11.00-12.00 by appointment via e-mail. Available also in other dates by appointment via e-mail |
Assigned to the Degree Course
| Date | Time | Classroom / Location |
|---|
| Date | Time | Classroom / Location |
|---|
Learning Objectives
The course is focused on acquiring the fundamental concepts of structural and metabolic biochemistry. The main aim of the course is to teach students the elements required to gain an understanding of the biochemical and molecular mechanisms of cellular metabolism, in order to provide the information needed to face subsequent courses.
In particular, an analysis will be carried out on the chemical reactions that allow living organisms to obtain energy by oxidizing organic molecules acquired from the diet and to transform these molecules into their constituents. Finally, the regulation mechanisms of such metabolic pathways in different physio-pathological conditions will be discussed.
Program
Introduction to Biochemistry.
Composition, structure and functions of proteins.
Enzymes:
Classification.
Structure.
Mechanisms of action
kinetic and regulation
Catalytic mechanisms and inhibition
Hemoglobin and myoglobin.
Chemistry of carbohydrates
Chemistry of lipids
Signal transduction
cAMP and calcium as second messengers.
Digestive processes: conversion of a meal in molecules used by the cell.
Basic notions on the metabolism.
Carbohydrate metabolism:
Glycolysis and gluconeogenesis.
Hexose monophosphate shunt.
Other sugars of metabolic interest.
Glycogen metabolism.
Lipid metabolism:
Beta oxidation.
Fatty acids synthesis.
Cholesterol metabolism.
Synthesis of triacylglycerol and phospholipids.
Metabolism of cholesterol.
Nitrogen metabolism:
Amino acids metabolism.
Urea cycle.
Amino acids biosynthesis.
Krebs cycle:
Functions, energy balance and regulation.
Oxidative phosphorylation:
The electron transport chain.
The proton motive force.
Regulation of metabolism.
Bridging Courses
Bridging courses are not required.
Learning Achievements (Dublin Descriptors)
Knowledge and ability of comprehension: The student must have acquired all the relevant knowledge about the structure and function of biological macromolecules and the basic principles that allow a full understanding of metabolism. The student must also have acquired basic knowledge about the metabolic regulation strategies, the specific biochemical processes of various tissues and organs, including their integration and hormonal regulation.
Ability to apply knowledge and comprehension: The student must demonstrate to be able to establish correlation between biological structure and function and to link the different studied topics.
Autonomy of judgement: The student must demonstrate to be able to critically evaluate the information received.
Communication skills: The student must demonstrate to be able to communicate the acquired skills by adequate scientific language.
Learning skill: The student must demonstrate to have developed good learning skills, enabling them to deepen the knowledge gained during the course by addressing subsequent study paths.
Teaching Material
The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it
Supporting Activities
Teaching materials and supporting activities are available through Moodle platform on line at blended.uniurb.it.
Teaching, Attendance, Course Books and Assessment
- Teaching
Frontal lessons.
- Attendance
The attendance is not mandatory, but strongly recommended.
- Course books
- NELSON, COX "I PRINCIPI DI BIOCHIMICA DI LEHININGER" (VIII ED) ZANICHELLI 2022
- BERG, TYMOCZKO, STRYER. BIOCHIMICA (VII ED) ZANICHELLI
- VOET & VOET "FONDAMENTI DI BIOCHIMICA" ZANICHELLI
- DEVLIN "BIOCHIMICA" con aspetti clinico-farmaceutici EdiSES
- Assessment
The exam consists of an oral exam with questions regarding the entire program of the course.
- Disability and Specific Learning Disorders (SLD)
Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.
To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.
Additional Information for Non-Attending Students
- Course books
- NELSON, COX "I PRINCIPI DI BIOCHIMICA DI LEHININGER" (VIII ED) ZANICHELLI 2022
- BERG, TYMOCZKO, STRYER. BIOCHIMICA (VII ED) ZANICHELLI
- VOET & VOET "FONDAMENTI DI BIOCHIMICA" ZANICHELLI
- DEVLIN "BIOCHIMICA" con aspetti clinico-farmaceutici EdiSES
- Assessment
The exam consists of an oral exam with questions regarding the entire program of the course.
- Disability and Specific Learning Disorders (SLD)
Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.
To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.
| « back | Last update: 19/02/2023 |
