CELLULAR GENE THERAPIES
TERAPIE GENICHE E CELLULARI
| A.Y. | Credits |
|---|---|
| 2022/2023 | 6 |
| Lecturer | Office hours for students | |
|---|---|---|
| Augusto Amici |
| Teaching in foreign languages |
|---|
|
Course with optional materials in a foreign language
English
This course is entirely taught in Italian. Study materials can be provided in the foreign language and the final exam can be taken in the foreign language. |
Assigned to the Degree Course
| Date | Time | Classroom / Location |
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| Date | Time | Classroom / Location |
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Learning Objectives
The course aims to provide students with the basic knowledge of Molecular Biology and to provide a cellular and molecular vision of modern innovative therapies, trying to deepen the methodologies used for the treatment of genetic diseases and disabling pathologies. Furthermore, the program will mention the modern techniques of anticancer immunotherapy.
Program
Gene therapies • What is gene therapy • Vectors used for gene therapy • Cancer immunotherapy a (DNA vaccination and phage vaccination) • Vaccines against infectious diseases (example of the creation of a sars-cov2 vaccine against multiple variants) • Car-T how they are obtained and their applications • Crisp/Cas9 system • Pre-clinical experimental cellular and animal models • Cellular Therapies • Totipotent, pluripotent and multipotent stem cells • Induced stem cells • How to obtain an organoid • Organoids as potential models for testing new biological and non-biological drugs
Bridging Courses
no propaedeutic
Learning Achievements (Dublin Descriptors)
D1 - Knowledge and understanding - Acquisition of the tools for understanding the pathogenetic mechanisms of the disease and the basic functioning of the immune system. Ability to use the specific language of this discipline. D2 - Ability to apply knowledge and understanding - Ability to recognize and apply the cognitive tools and methodological rigor of General Pathology and Immunology for the rational exercise of any activity connected directly and indirectly to health protection. D3 - Making judgments - Being able to autonomously evaluate the results of studies aimed at clarifying the pathogenetic and diagnostic mechanisms of diseases D4 - Communication skills - Ability to explain the knowledge acquired in a simple, immediate and exhaustive manner as well as knowing how to interface with the future professional reality (researchers, students, health professionals). D5 - Learning ability - Ability to update by consulting the scientific publications of the discipline in question. Ability to participate, using the knowledge acquired in the course, in continuous updating initiatives in the professional field.
Teaching Material
The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it
Teaching, Attendance, Course Books and Assessment
- Teaching
The course includes lectures in which the teacher explains the fundamental concepts and provides practical examples to facilitate understanding. Students are encouraged to intervene during the lessons both to request clarifications from the teacher and to provide further insights or topics of interest to them.
- Attendance
Obligations Class attendance is recommended but not mandatory.
- Course books
The teacher does not deem it necessary to use textbooks, the material provided by the teacher is sufficient for the study
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