The course of Epigenetics and basics of role in human diseases aims to provide students the basic information of the epigenetic mechanisms and their role in the development of human diseases. 

1. Introduction to Epigenetics

2. The basis of transcription process

3. DNA packging and chromatin architecture

4. Chromatin remodeling 

5. DNA methylation and experimental approaches

6. Histone post-translational modifications (HPTMs)

7. Histone modifications machinery

8. Chromatin Imunoprecipitation: ChIP

9 Non coding RNA: an intro

10. Epigenetics of cancer

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Knowledge and understanding - Acquisition of the tools to understand the mechanisms of disease. Ability to use the language of their specific discipline.

Applying knowledge and understanding - Ability to recognize and apply the cognitive tools and the rigorous approach of the Epigenetic as rational of any activity related directly and indirectly to health protection.

Indipendence of judgment - Being able to learn and independently evaluate the results of investigations on epigenrtic related to both physiological and pathological models 

Communicative skills - Ability to explain, in a simple, immediate and exhaustive manner the acquired knowledge and to know how to interface with future professional roles (researchers, students, health-operative).

Learning ability - Upgrade capabilities through consultation of the scientific literatue of the discipline. Ability to participate, using the knowledge gained in the course, the continuous updating initiatives in the professional field.

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

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Teaching

Lectures

Attendance

No obligation

Course books

- EPIGENETICA - Massimo Romani - Zanichelli

or

- EPIGENETICS - Lyle Armstrong - Garland Science

(additional material will be provided by the lecturer)

Assessment

The final assessment of learning includes only a written test aimed at verifying the understanding of the key topics of epigenetic processes both in the physiological and pathological framework. The student will be asked 30 questions (in the form of multiple choice and open questions) distributed over the entire teaching program through the University Blended Learning platform.

Disability and Specific Learning Disorders (SLD)

Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.

Teaching

Lectures

Attendance

No obligation

Course books

- EPIGENETICA - Massimo Romani - Zanichelli

or

- EPIGENETICS - Lyle Armstrong - Garland Science

(additional material will be provided by the lecturer)

Assessment

The final assessment of learning includes only a written test aimed at verifying the understanding of the key topics of epigenetic processes both in the physiological and pathological framework. The student will be asked 30 questions (in the form of multiple choice and open questions) distributed over the entire teaching program through the University Blended Learning platform.

Disability and Specific Learning Disorders (SLD)

Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.